Major Depressive Disorder and Mood Disorders
Major Depressive Disorder (MDD) is one of the most commonly tested psychiatric conditions on the NCLEX-RN. To meet diagnostic criteria, a patient must experience at least five symptoms during a two-week period.
Key MDD Symptoms
These symptoms include depressed mood or loss of interest or pleasure, plus at least three others:
- Changes in appetite or weight
- Sleep disturbance
- Fatigue or loss of energy
- Feelings of worthlessness
- Difficulty concentrating
- Recurrent thoughts of death
The DSM-5 specifies that symptoms must cause clinically significant distress or impairment in functioning. This distinction separates sadness from clinical depression.
Related Mood Disorders
Persistent Depressive Disorder (dysthymia) is chronic depression lasting at least two years in adults. Bipolar Disorder involves alternating episodes of mania or hypomania and depression. During manic episodes, patients experience grandiosity, decreased need for sleep, racing thoughts, flight of ideas, distractibility, and increased goal-directed activity.
Nursing Care and Treatment
Focus your care on safety assessment, especially suicide risk. Establish therapeutic relationships and encourage self-care activities. Administer antidepressants like SSRIs and SNRIs, and monitor medication side effects closely.
Electroconvulsive Therapy (ECT) remains an important option for severe depression unresponsive to medications. Antidepressants take two to four weeks to become effective, which is critical for patient teaching.
Anxiety Disorders and Their Nursing Management
Anxiety disorders share excessive worry or fear as primary symptoms but differ in triggers and presentation. Understanding these distinctions is essential for the NCLEX-RN.
Common Anxiety Disorders
Generalized Anxiety Disorder (GAD) involves persistent worry about multiple aspects of daily life for at least six months. Panic Disorder features recurrent unexpected panic attacks with sudden intense fear, rapid heartbeat, shortness of breath, chest pain, and dizziness.
Social Anxiety Disorder involves fear of social situations where embarrassment might occur. Specific Phobias involve intense fear of particular objects or situations. Agoraphobia involves fear of situations where escape might be difficult, often paired with panic disorder.
Post-Traumatic Stress Disorder (PTSD)
PTSD develops following exposure to actual or threatened death, serious injury, or sexual violence. Symptoms include intrusive memories, nightmares, avoidance behaviors, negative mood changes, and hyperarousal symptoms.
Treatment Approaches
First-line treatments are Cognitive Behavioral Therapy (CBT) and SSRIs like sertraline and paroxetine. Benzodiazepines provide short-term symptom relief but carry addiction risks. Use them cautiously.
Nursing Interventions
Create safe environments and teach grounding techniques like the 5-4-3-2-1 sensory method. Encourage deep breathing and progressive muscle relaxation. Validate patient experiences and support psychotherapy. For NCLEX preparation, distinguish between normal anxiety and anxiety disorders, and know both pharmacological and non-pharmacological interventions.
Schizophrenia Spectrum Disorders and Psychosis
Schizophrenia is a severe psychiatric disorder affecting approximately one percent of the population. It involves three main symptom categories: positive, negative, and cognitive symptoms.
Positive Symptoms
Positive symptoms are experiences added to normal functioning. Hallucinations are false perceptions occurring without external stimuli, most commonly auditory in schizophrenia. Delusions are fixed, false beliefs resistant to contradictory evidence, including paranoid, grandiose, somatic, and nihilistic types.
Disorganized speech reflects disrupted thought processes and may include tangentiality, circumstantiality, or word salad. Disorganized behavior includes unusual movements or catatonia.
Negative and Cognitive Symptoms
Negative symptoms represent diminished emotional expression, avolition (lack of motivation), and alogia (poverty of speech). These symptoms are harder to treat than positive symptoms.
Cognitive symptoms involve problems with working memory, attention, and executive function. These affect daily functioning significantly.
Related Conditions
Brief Psychotic Disorder lasts one to four weeks. Schizophreniform Disorder lasts one to six months. Schizoaffective Disorder combines schizophrenic symptoms with mood episodes. Duration determines diagnosis, so memorize these timeframes.
Antipsychotic Medications
Typical (first-generation) antipsychotics like haloperidol are less expensive but carry higher risks of extrapyramidal side effects: akathisia, dystonia, and tardive dyskinesia. These movement disorders are serious.
Atypical (second-generation) antipsychotics like risperidone, olanzapine, and quetiapine have fewer movement disorders but pose metabolic risks like weight gain and hyperglycemia. Know the trade-offs between these drug classes.
Nursing Care Strategies
Establish trust despite the patient's paranoia. Avoid defensive responses to accusations. Provide structure and simple explanations. Monitor for medication compliance and side effects. Coordinate comprehensive treatment including psychosocial interventions and rehabilitation programs.
Personality Disorders and Cluster Classifications
Personality disorders represent enduring, inflexible patterns of thinking, feeling, and behaving that deviate markedly from cultural expectations. These patterns cause significant distress or impairment and persist across time and situations.
The Three Clusters
DSM-5 organizes personality disorders into three clusters:
- Cluster A (odd, eccentric): Paranoid, Schizoid, and Schizotypal Personality Disorders
- Cluster B (dramatic, emotional, erratic): Antisocial, Borderline, Histrionic, and Narcissistic Personality Disorders
- Cluster C (anxious, fearful): Avoidant, Dependent, and Obsessive-Compulsive Personality Disorders
Memorize these clusters for quick recall on the NCLEX-RN.
Borderline Personality Disorder (BPD)
BPD frequently appears on exams. It features pervasive instability in relationships, self-image, and emotion, combined with impulsive behaviors like substance abuse, binge eating, or reckless spending. Patients often fear abandonment and may alternate between idealization and devaluation of others. Recurrent suicidal behaviors or self-harm are common.
Antisocial and Narcissistic Personality Disorders
Antisocial Personality Disorder involves persistent violation of others' rights, deceitfulness, impulsivity, irritability, aggression, recklessness, and lack of remorse. Narcissistic Personality Disorder features grandiose sense of self-importance, preoccupation with fantasies of success or power, and exploitativeness.
Treatment Approaches
Unlike other psychiatric disorders, personality disorders lack specific medications. Treatment involves psychotherapy approaches like Dialectical Behavior Therapy (DBT) for BPD, focusing on acceptance and change. These are long-term treatments requiring patient commitment.
Nursing Considerations
Require clear boundaries, consistency, and avoid emotional reactions to manipulative or provocative behavior. Recognize that personality disorders are difficult to treat. Maintain professional distance while remaining compassionate.
Substance-Related and Addictive Disorders
Substance-Related and Addictive Disorders involve problematic use of alcohol, opioids, stimulants, sedatives, hallucinogens, and other drugs, as well as gambling disorder. Substance Use Disorder requires meeting criteria related to impaired control, social impairment, risky use, and pharmacological criteria.
Understanding Tolerance and Withdrawal
Tolerance occurs when increasing amounts of a substance are needed to achieve the desired effect. Withdrawal involves physical and psychological symptoms when substance use decreases or stops. Withdrawal syndromes vary significantly by substance type.
Alcohol Use Disorder
Alcohol Use Disorder ranges from mild to severe. It can lead to serious medical complications including cirrhosis, pancreatitis, peripheral neuropathy, and Wernicke-Korsakoff syndrome. Alcohol withdrawal can be life-threatening with seizures and delirium tremens, requiring medical management.
Opioid and Stimulant Disorders
Opioid Use Disorder creates intense physical dependence with withdrawal symptoms like anxiety, insomnia, body aches, and gastrointestinal distress. Stimulant use disorders involving cocaine and methamphetamine produce intense euphoria followed by crashes that drive continued use. Opioid withdrawal is extremely uncomfortable but not typically life-threatening.
Treatment Modalities
Treatment approaches include medication-assisted treatment (methadone, buprenorphine for opioids), cognitive behavioral therapy, motivational interviewing, peer support groups like Alcoholics Anonymous, and residential rehabilitation programs. Benzodiazepine withdrawal, like alcohol withdrawal, requires medical supervision.
Nursing Assessment and Care
Obtain detailed substance use history and monitor for withdrawal symptoms. Provide supportive care and administer medications as prescribed. Connect patients with treatment resources. Recognize that substance-related disorders are medical conditions requiring compassionate, evidence-based care rather than judgment.
