Taxonomy, Cell Biology, and Genetics Mnemonics
Introductory biology's biggest memorization hurdles are the taxonomic hierarchy, the stages of mitosis and meiosis, and the central dogma. These mnemonics compress all three into phrases you can recall instantly.
Taxonomic Classification
Taxonomic Hierarchy: Use 'King Philip Came Over For Good Spaghetti' for Kingdom, Phylum, Class, Order, Family, Genus, Species. For the updated three-domain system, add Domain at the start: 'Dear King Philip Came Over For Good Spaghetti'.
Domains of Life: Remember 'Bacteria Are Everywhere' for the three domains. Bacteria and Archaea are prokaryotes. Eukarya includes all organisms with membrane-bound nuclei.
Cell Division
Mitosis Phases: Use 'PMAT' for the four phases: Prophase, Metaphase, Anaphase, Telophase. Add Interphase before and Cytokinesis after for the complete cell cycle.
Mitosis Details: Prophase (chromosomes condense, nuclear envelope breaks). Metaphase (Middle: chromosomes align at equator). Anaphase (Apart: sister chromatids separate). Telophase (Two: two nuclei reform).
Meiosis Separation: In Meiosis I, homologous chromosomes separate. In Meiosis II, sister chromatids separate. Remember that Meiosis I includes crossing over in Prophase I, creating genetic variation.
DNA and Protein Synthesis
DNA Base Pairing: Use 'Apples in Tree, Cars in Garage' for Adenine-Thymine (2 hydrogen bonds) and Cytosine-Guanine (3 hydrogen bonds). In RNA, Adenine pairs with Uracil instead of Thymine.
Central Dogma: DNA replicates to DNA. DNA transcribes to RNA. RNA translates to protein. Remember 'Don't Rip People' as the shorthand. Retroviruses are the exception with reverse transcription.
Stop Codons: Use 'U Are Away, U Are Gone, U Go Away' for UAA, UAG, and UGA. The start codon is AUG, which codes for methionine.
Inheritance Patterns
Punnett Square Ratios: Monohybrid crosses (Aa × Aa) produce a 3:1 phenotype ratio and 1:2:1 genotype ratio. Dihybrid crosses (AaBb × AaBb) produce a 9:3:3:1 ratio.
Meiosis Variation Sources: Use 'CRAM' for the four sources of genetic diversity. Crossing over, Random assortment, Alignment at metaphase I, and Mutation all increase variation within species.
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Taxonomic Hierarchy: 'King Philip Came Over For Good Spaghetti', Kingdom, Phylum, Class, Order, Family, Genus, Species. Add Domain in front for the updated three-domain system: 'Dear King Philip Came Over For Good Spaghetti'.
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Domains of Life: Bacteria, Archaea, Eukarya. 'Bacteria Are Everywhere', all three have cellular life; Archaea include extremophiles; Eukarya have membrane-bound nuclei.
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Mitosis Phases: 'PMAT', Prophase, Metaphase, Anaphase, Telophase. Add Interphase before and Cytokinesis after for the full cell cycle.
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Meiosis I (Reductional): 'Homologs separate.' Meiosis II (Equational): 'Sisters separate.' Meiosis I goes through PMAT I with crossing over in Prophase I.
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Mitosis Detail: Prophase (chromosomes condense, envelope breaks); Metaphase (Middle, align at equator); Anaphase (Apart, sister chromatids separate); Telophase (Two, two nuclei reform).
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DNA Bases Pairing: 'Apples in Tree, Cars in Garage', Adenine-Thymine (2 H-bonds); Cytosine-Guanine (3 H-bonds). In RNA: Adenine-Uracil, Cytosine-Guanine.
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Central Dogma: DNA → RNA → Protein. 'Don't Rip People', DNA is replicated, transcribed to RNA, translated to protein. Reverse transcription (retroviruses) is the exception.
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Stop Codons: 'U Are Away, U Are Gone, U Go Away', UAA, UAG, UGA. Start codon: AUG (methionine).
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Punnett Square Ratios: Monohybrid Aa × Aa → 3:1 phenotype, 1:2:1 genotype. Dihybrid AaBb × AaBb → 9:3:3:1. 'Three-one, nine-three-three-one'.
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Meiosis Variation Sources: 'CRAM', Crossing over, Random assortment, Alignment at metaphase I, Mutation. Produces genetic diversity within a species.
Human Anatomy Mnemonics
Anatomy and physiology courses rank among the most memorization-heavy health sciences classes. These classic mnemonics cover the most-tested structures in the nervous, skeletal, and muscular systems.
Cranial Nerves
Cranial Nerve Names (I-XII): Use 'Oh Oh Oh To Touch And Feel Very Good Velvet, Ah Heaven'. This encodes Olfactory, Optic, Oculomotor, Trochlear, Trigeminal, Abducens, Facial, Vestibulocochlear, Glossopharyngeal, Vagus, Accessory, and Hypoglossal.
Cranial Nerve Function: Add 'Some Say Marry Money, But My Brother Says Big Brains Matter Most' where S equals Sensory, M equals Motor, and B equals Both. This second mnemonic tells you whether each nerve has sensory, motor, or mixed function.
Skeletal System
Carpal Bones: Use 'Some Lovers Try Positions That They Can't Handle' for the wrist bones in order. This gives you Scaphoid, Lunate, Triquetrum, Pisiform, Trapezium, Trapezoid, Capitate, and Hamate.
Tarsal Bones: Remember 'Tiger Cubs Need MILC' for the foot bones. This covers Talus, Calcaneus, Navicular, Medial cuneiform, Intermediate cuneiform, Lateral cuneiform, and Cuboid.
Muscles
Rotator Cuff: Use 'SITS' for the four shoulder muscles that stabilize the joint. Supraspinatus, Infraspinatus, Teres minor, and Subscapularis support arm rotation and stability.
Brachial Plexus Organization: Remember 'Real Teenagers Drink Cold Beer' for Roots, Trunks, Divisions, Cords, and Branches. This traces how spinal nerves organize into terminal nerves.
Extraocular Muscles: Use 'LR6 SO4 3' to remember which cranial nerve controls each eye muscle. Lateral Rectus uses CN VI. Superior Oblique uses CN IV. All others use CN III.
Integumentary and Other Systems
Skin Layers: Use 'Come Let's Get Sun Burned' for the five epidermis layers from outermost to innermost. Corneum, Lucidum, Granulosum, Spinosum, Basale.
Abdominal Quadrants: 'Liver Gall Duo' helps you remember right upper quadrant organs. Liver, Gallbladder, Duodenum, right kidney, and pancreas head occupy the RUQ.
Spinal Nerve Count: Remember '8, 12, 5, 5, 1' for cervical, thoracic, lumbar, sacral, and coccygeal nerves. Use 'Breakfast at 8, lunch at 12, dinner at 5, dessert at 5, bedtime at 1' as a memory aid.
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Cranial Nerves (I-XII): 'Oh Oh Oh To Touch And Feel Very Good Velvet, Ah Heaven', Olfactory, Optic, Oculomotor, Trochlear, Trigeminal, Abducens, Facial, Vestibulocochlear, Glossopharyngeal, Vagus, Accessory, Hypoglossal.
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Cranial Nerve Function: 'Some Say Marry Money, But My Brother Says Big Brains Matter Most', S=Sensory, M=Motor, B=Both. Sequence gives function of each of the 12 nerves.
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Carpal Bones: 'Some Lovers Try Positions That They Can't Handle', Scaphoid, Lunate, Triquetrum, Pisiform, Trapezium, Trapezoid, Capitate, Hamate. Proximal row then distal row.
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Tarsal Bones: 'Tiger Cubs Need MILC', Talus, Calcaneus, Navicular, Medial cuneiform, Intermediate cuneiform, Lateral cuneiform, Cuboid.
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Rotator Cuff: 'SITS', Supraspinatus, Infraspinatus, Teres minor, Subscapularis. Four muscles stabilizing the shoulder.
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Layers of Skin: 'Come Let's Get Sun Burned', Corneum, Lucidum, Granulosum, Spinosum, Basale. Outermost to innermost layers of the epidermis.
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Abdominal Quadrants (RUQ organs): 'Liver Gall Duo', Liver, Gallbladder, Duodenum, Right kidney, Head of pancreas. Useful for physical exam findings.
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Brachial Plexus: 'Real Teenagers Drink Cold Beer', Roots, Trunks, Divisions, Cords, Branches. Order of organization from spinal cord to terminal nerves.
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Extraocular Muscles: 'LR6 SO4 3', Lateral Rectus by CN VI, Superior Oblique by CN IV, all others by CN III. Classic medical school mnemonic for eye movement.
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Spinal Nerve Count: 8 Cervical, 12 Thoracic, 5 Lumbar, 5 Sacral, 1 Coccygeal = 31 pairs. 'Breakfast at 8, lunch at 12, dinner at 5, dessert at 5, bedtime at 1'.
Physiology, Biochemistry, and Microbiology Mnemonics
These mnemonics target the functional side of biology. Metabolic pathways, hormone actions, and microbial characteristics show up repeatedly on exams from AP Bio through the MCAT and USMLE.
Hormones and Amino Acids
Anterior Pituitary Hormones: Use 'FLAT PiG' for the six hormones. FSH, LH, ACTH, TSH, Prolactin, and GH are all produced by the anterior pituitary gland.
Essential Amino Acids: Remember 'PVT TIM HALL' for the nine essential amino acids. Phenylalanine, Valine, Threonine, Tryptophan, Isoleucine, Methionine, Histidine, Arginine (in children), Leucine, and Lysine. Your body cannot synthesize these, so you must obtain them from food.
Metabolic Pathways
Krebs Cycle Intermediates: Use 'Citrate Is Krebs Starting Substrate For Making Oxaloacetate'. This gives you all eight intermediates in order: Citrate, Isocitrate, α-Ketoglutarate, Succinyl-CoA, Succinate, Fumarate, Malate, and Oxaloacetate.
Glycolysis Products: Remember that glucose produces a net of 2 ATP, 2 NADH, and 2 pyruvate molecules. Think of it as 'Glucose Gives 2 Pieces of Energy' to track the energy molecules produced.
Electron Transport Chain: Use 'Flavins Carry Complexes, Q, C, OH' to remember the sequence. This represents Complex I (NADH dehydrogenase), Complex II (succinate dehydrogenase), Coenzyme Q, Complex III, Cytochrome C, Complex IV, and Oxygen. The chain produces water and generates ATP through chemiosmosis.
Tissues and Blood Cells
Four Tissue Types: Use 'NEMC' to remember every organ's building blocks. Nervous tissue, Epithelial tissue, Muscle tissue, and Connective tissue make up all human organs.
Blood Cell Lineage: Remember 'Eric Never Bathes, Mostly Lounges, Lying on Many Beaches' for blood cells and their origins. This gives you Erythrocyte, Neutrophil, Basophil, Monocyte, Lymphocyte, Lymph node, Megakaryocyte, and Bone marrow.
Antibody Isotypes: Use 'MADGE' for the five immunoglobulin classes. IgM (first immune response), IgA (mucosal immunity), IgD (B cell surface marker), IgG (most abundant), and IgE (allergic response).
Microbiology
Gram Staining: 'Positive stains Purple, Negative is Pink' helps you remember staining results. Gram-positive bacteria have a thick peptidoglycan layer that retains crystal violet. Gram-negative bacteria have a thin layer and appear red or pink.
Bacterial Virulence Factors: Use 'CAPS' for the major virulence factors. Capsule (prevents phagocytosis), Adhesins (attach to host), Pili (cell-to-cell contact), and Spores (survive harsh conditions).
Obligate Anaerobes: Remember 'Can't Breathe Fresh Air' for bacteria that cannot tolerate oxygen. Clostridium, Bacteroides, Fusobacterium, and Actinomyces all require anaerobic environments.
Hepatitis Transmission: Use 'A E equals Enteral, B C D equals Blood'. Hepatitis A and E spread through contaminated food and water via fecal-oral routes. Hepatitis B, C, and D spread through blood contact and sexual transmission.
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Pituitary Hormones (Anterior): 'FLAT PiG', FSH, LH, ACTH, TSH, Prolactin, GH. All six hormones of the anterior pituitary.
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Essential Amino Acids: 'PVT TIM HALL', Phenylalanine, Valine, Threonine, Tryptophan, Isoleucine, Methionine, Histidine, Arginine (in kids), Leucine, Lysine. Nine essential, or ten if counting arginine.
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Kreb's Cycle Intermediates: 'Citrate Is Krebs Starting Substrate For Making Oxaloacetate', Citrate, Isocitrate, α-Ketoglutarate, Succinyl-CoA, Succinate, Fumarate, Malate, Oxaloacetate.
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Glycolysis Products: Net 2 ATP, 2 NADH, 2 pyruvate per glucose. 'Glucose Gives 2 Pieces of Energy', glucose (6C) split into two pyruvates (3C).
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Electron Transport Chain: 'Flavins Carry Complexes, Q, C, OH', Complex I (NADH dehydrogenase), Complex II (succinate dehydrogenase), CoQ, Complex III, Cyt c, Complex IV, O2. Produces H2O and ATP via chemiosmosis.
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Four Tissue Types: 'NEMC', Nervous, Epithelial, Muscle, Connective. Every organ is built from these four.
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Blood Cell Lineage: 'Eric Never Bathes, Mostly Lounges, Lying (on) Many Beaches', Erythrocyte, Neutrophil, Basophil, Monocyte, Lymphocyte, Lymph node, Megakaryocyte, Bone marrow. Order and origin of blood cells.
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Antibody Isotypes: 'MADGE', IgM, IgA, IgD, IgG, IgE. Five immunoglobulin classes; know functions (M first response, G most abundant, E allergy, A mucosal, D surface).
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Gram-Positive vs. Gram-Negative: 'Positive stains Purple, Negative is Pink', peptidoglycan layer traps crystal violet in Gram+; Gram− stains counterstain red/pink.
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Virulence Factors of Bacteria: 'CAPS', Capsule, Adhesins, Pili, Spores. Plus exotoxins/endotoxins for pathogenic effects.
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Obligate Anaerobes: 'Can't Breathe Fresh Air', Clostridium, Bacteroides, Fusobacterium, Actinomyces. Cannot tolerate oxygen.
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Hepatitis Transmission: 'A E = Enteral (fecal-oral), B C D = Blood/sex'. Hep A and E via contaminated food/water; B, C, D via bodily fluids and sex.
Ecology and Evolution Mnemonics
These mnemonics often get overlooked but still appear repeatedly on AP Bio, intro ecology, and the MCAT. They compress key categories and requirements into single memorable phrases.
Evolution and Natural Selection
Hardy-Weinberg Conditions: Recall five conditions required for no evolution to occur. No selection, mutation, migration, mating bias, or small population effects. If any condition fails, allele frequencies change over generations.
Natural Selection Requirements: Use 'VIP' for the three essential ingredients. Variation (traits differ among individuals), Inheritance (traits are heritable), and differential Production (some organisms have more reproductive success). All three must be present for adaptation.
Evidence for Evolution: Remember 'Fossils Home Biogeography Directly Molecules' for the major lines of evidence. Fossil record, Homologous structures, Biogeography, Direct observation of evolution, and Molecular sequence similarity all support evolutionary theory.
Population Ecology
r versus K Selection: r-selected species include rabbits and insects. They have many offspring with little parental care. K-selected species include elephants and humans. They have few offspring with high parental investment. Think 'r equals rapid reproduction, K equals careful parenting'.
Symbiotic Relationships: Five main relationships exist between organisms. Mutualism (+/+) benefits both. Commensalism (+/0) benefits one. Parasitism (+/negative) harms one. Competition (negative/negative) harms both. Predation (+/negative) benefits predator.
Ecosystems and Biogeochemistry
Biogeochemical Cycles: Use 'CHNOPS' for the six most abundant elements in living organisms. Carbon, Hydrogen, Nitrogen, Oxygen, Phosphorus, and Sulfur cycle through ecosystems and living things.
Trophic Levels and Energy: Remember the sequence as Producers arrow Primary consumers (herbivores) arrow Secondary consumers arrow Tertiary consumers. Apply the 10% rule: only about 10% of energy passes to the next trophic level. Most energy is lost as heat.
Community Succession
Succession Stages: Primary succession begins on bare rock. Pioneer species (lichens and mosses) arrive first. Then grasses grow, then shrubs, then softwood trees, then hardwood trees reach the climax community. Secondary succession skips the pioneer phase on previously vegetated land.
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Hardy-Weinberg Conditions: 'No Selection, Mutation, Migration, Mating bias, or small population.' Five conditions for no evolution. If any fails, allele frequencies change.
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Natural Selection Requirements: 'VIP', Variation (in traits), Inheritance (heritable), differential Production (reproductive success). All three required for adaptation.
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Symbioses: Mutualism (+/+), Commensalism (+/0), Parasitism (+/−), Competition (−/−), Predation (+/−). 'Mutually Mighty, Competitively Costly'.
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Biogeochemical Cycles: 'CHNOPS', the six most abundant elements in living organisms: Carbon, Hydrogen, Nitrogen, Oxygen, Phosphorus, Sulfur. All cycle through ecosystems.
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Trophic Levels: Producers → primary consumers (herbivores) → secondary consumers → tertiary. 10% rule: only ~10% of energy passes up each level. 'Pigs Prefer Some Tasty Treats'.
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Evidence for Evolution: 'Fossils Home Biogeography Directly Molecules', Fossil record, Homologous structures, Biogeography, Direct observation, Molecular sequence similarity.
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r vs. K Selection: r-selected (rabbits, insects), many offspring, little care. K-selected (elephants, humans), few offspring, high parental investment. 'r = rapid, K = careful'.
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Succession Stages: Primary (bare rock) → pioneer species (lichens, mosses) → grasses → shrubs → softwoods → hardwoods (climax community). Secondary skips pioneer phase.
How to Build Biology Mnemonics That Stick
The mnemonics above are excellent starters, but the most memorable ones are personal. Here's how to build biology mnemonics that stick and pair them with spaced repetition for long-term recall.
Building Your Own Mnemonics
Step 1: Identify what you need to memorize. Biology is full of ordered sequences like taxonomy, cranial nerves, and metabolic pathways. First-letter mnemonics work best for these lists.
Step 2: Extract first letters from each item. Try rearranging letters into a pronounceable acronym if order doesn't matter. Otherwise, build an acrostic sentence where each word starts with the target letter.
Step 3: Make it vivid, absurd, or personal. 'Some Lovers Try Positions That They Can't Handle' sticks much better than 'Scaphoid Lunate Triquetrum Pisiform Trapezium Trapezoid Capitate Hamate'. Emotion and absurdity boost memory encoding.
Enhancing Mnemonic Power
Pair mnemonics with visuals when possible. Medical students memorizing cranial nerves often sketch a face with each nerve labeled. The mnemonic plus the drawing create dual-coded memory that's stronger than words alone.
Create layered mnemonics for complex topics. Use one mnemonic for the overall list and another for sub-items. A med student memorizing all 12 cranial nerves might use one mnemonic for names and a second for sensory/motor/both function.
Integrating With Spaced Repetition
Put the mnemonic on one flashcard side and the full list on the other. For example: front shows 'King Philip Came Over For Good Spaghetti', back shows the seven taxonomic ranks. When FluentFlash presents the mnemonic, you retrieve both the phrase and the underlying list.
Review in both directions. Build cards that ask for the mnemonic from the topic, and others that ask for the full list from the mnemonic. This double retrieval exercise strengthens memory twice per review.
Use FSRS scheduling to surface each card at the optimal interval. FluentFlash's algorithm shows cards just before they fade from memory, maximizing long-term retention. Over a semester, this turns clever one-time tricks into permanent recall.
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Identify the list, pathway, or sequence you need to memorize. Biology is full of ordered sequences (taxonomy, cranial nerves, metabolic pathways) where first-letter mnemonics work best.
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Extract the first letter of each item. Try to rearrange (if order doesn't matter) into a pronounceable acronym, or build an acrostic sentence where each word starts with the target letter.
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Make it vivid, absurd, or personal. 'Some Lovers Try Positions That They Can't Handle' sticks in ways that 'Scaphoid Lunate Triquetrum Pisiform Trapezium Trapezoid Capitate Hamate' never will.
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Tie mnemonics to visuals when possible. Medical students learning cranial nerves often sketch a face with each nerve labeled, the mnemonic plus the drawing creates a dual-coded memory.
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Put the mnemonic on one side of a FluentFlash card and the full list on the other. Review in both directions: mnemonic → list, and list → mnemonic. FSRS scheduling surfaces each card just before it fades.
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Use layered mnemonics for complex topics, one mnemonic for the overall list, another for sub-items. A med student memorizing all 12 cranial nerves might use one mnemonic for the names and a second for sensory/motor/both function.
